CORNEAL THICKNESS AND VOLUME IN SUBCLINICAL AND CLINICAL KERATOCONUS

Title CORNEAL THICKNESS AND VOLUME IN SUBCLINICAL AND CLINICAL KERATOCONUS
Author, Co-Author Seyed Mahdi Ahmadi Hosseini, Fereshteh Abolbashari, Norhani Mohidin, Bariah Mohamad Ali
Topic
Year
2012
Day
Program Number
125070
Room
Exhibit Hall E
Affiliation
Abstract PURPOSE: To compare the corneal thickness and volume in subclinical and clinical keratoconus of Asian population in order to better discrimination between normal and ectatic cornea.

METHODS: Eyes were placed into one of the following group according to our patient grouping criteria: normal, subclinical and mild-moderate keratoconus. Pentacam Scheimpflug imaging (Oculus Inc., Wetzlar, Germany) was performed for the subject to record thinnest corneal thickness, central corneal thickness, corneal thickness (CT) and percentage thickness increase (PTI) at 2, 4, 6 and 8 mm and corneal volume (CV). Then data were exported to SPSS for statistical analysis.

RESULTS: Subjects comprised 32 mild to moderate clinical keratoconus, 15 subclinical keratoconus and 52 normal eyes. Our results indicated CT distribution, PTI and CV were significantly different in normal compare to subclinical and clinical keratoconus (P<.05). Overall subclinical group showed less CT distribution and volume, and more PTI compare to normal. In contrast, they showed more CT distribution and volume, and less PTI compare to keratoconus group. In addition, from thinnest point of the cornea to periphery we faced to less change in the PCT and PTI.

CONCLUSIONS: To the best of our knowledge, this is the first study that record the CT distribution and CV profile in subclinical and clinical keratoconus of Asian population. The results indicated that CT parameters and CV were significantly different in normal versus subclinical and normal versus keratoconus. These findings can help clinicians to better discriminate between normal and ecstatic cornea.
Affiliation of Co-Authors
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