DETECTION OF DIFFERENCES IN THE RETINAL NERVE FIBER LAYER (RNFL) THICKNESS IN NORMAL AND GLAUCOMATOUS EYES OF BLACK SUBJECTS

Title DETECTION OF DIFFERENCES IN THE RETINAL NERVE FIBER LAYER (RNFL) THICKNESS IN NORMAL AND GLAUCOMATOUS EYES OF BLACK SUBJECTS
Author, Co-Author Ricky Alaniz, Charles Wormington
Topic
Year
1998
Day
Sunday
Program Number
Poster 33
Room
Grand Ballroom
Affiliation
Abstract PURPOSE. To measure the RNFL thickness in black patients with obvious glaucomatous defects and compare that to the RNFL thickness in normal black subjects and to the normal database in the new GDx Nerve Fiber Analyzer.

METHODS. The right eye from each of 13 glaucomatous black patients and 13 age-matched normal black subjects was imaged with the new GDx Nerve Fiber Analyzer (Laser Diagnostic Technologies, Inc., San Diego, CA). Mean age of the glaucomatous (normal) subjects +/- SD was 54 +/- 12 (43 +/- 15) years with a range of 33-78 (27-78) years. Three polarization images were obtained from a 15 deg retinal area centered on the optic nerve head (ONH). The phase shift in the polarization was measured in an annulus 1.75 disc diameters from the ONH. Analysis included breaking the annulus up into 4 sectors (temporal: 0-25 and 335-360 deg; superior: 25-135 deg; nasal: 135-215 deg; and inferior: 215-335 deg) as well as 36 wedges 10 deg wide. Red-free fundus photos and threshold visual fields were obtained from all subjects.

RESULTS. The measured mean RNFL thickness +/- SD in glaucoma (normal) subjects for the superior, inferior, nasal and temporal sectors was 77 +/- 21 (85 +/- 17), 75 +/- 16 (92 +/- 17), 61 +/- 18 (69 +/- 19), and 46 +/- 7 (57 +/- 8) micrometers, respectively. Using the single-factor ANOVA, only the inferior sector difference reached the level of statistical significance (p THE EFFECT OF ENVIRONMENTAL CONDITIONS ON PH AND OSMOLALITY OF GLAUCOMA MEDICATIONS
Affiliation of Co-Authors
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