DEVELOPMENT OF A METHOD TO ASSESS THE CLEANING EFFICACY OF DAILY CLEANERS UTILIZING SONICATION AND VIDEO IMAGE ANALYSIS

Title DEVELOPMENT OF A METHOD TO ASSESS THE CLEANING EFFICACY OF DAILY CLEANERS UTILIZING SONICATION AND VIDEO IMAGE ANALYSIS
Author, Co-Author Bahram Asgharian, Thierry Bilbault, Masood Chowhan
Topic
Year
1992
Day
Sunday
Program Number
Poster 17
Room
Great Hall
Affiliation
Abstract An objective method was developed to assess the cleaning efficacy of daily cleaners. The method uses a lipid-protein mixed deposition model containing the major lipids and protein fractions of the human lacrimal secretion. Sonication is utilized as a reproducible, uniform source for mechanical energy which eliminates the variability associated with manual rubbing. The extent of deposit on lenses is analyzed using an objective video image analysis system. The rate and the extent of cleaning of in vitro deposited lenses following multiple sonication cycles in test solutions is monitored. An application of this method to assess the cleaning efficacies of formulations is presented using FDA Group I soft contact lenes. Results demonstrate that the method is capable of reproducibly differentiating the cleaning efficacy of daily cleaners.
Affiliation of Co-Authors
Outline