MODIFICATION OF ANTERIOR EYE DEVELOPMENT

Title MODIFICATION OF ANTERIOR EYE DEVELOPMENT
Author, Co-Author Noel Brennan, Genevieve Napper, Margaret Squires, Glenn Vessey, Algis Vingrys
Topic
Year
1992
Day
Monday
Program Number
1:45 pm
Room
Scotland B
Affiliation
Abstract Compelling evidence exists for an emmetropization procedure that regulates growth of the vitreous chamber in response to the visual environment. There is also evidence, albeit less convincing, for a separate environmentally controlled mechanism that governs the development of the anterior eye. We have examined the relationship between the visual environment and anterior eye development in the chick eye model. Central corneal curvature and anterior chamber depths of chick eyes were monitored by a modified keratometry technique and ultrasonography for up to five weeks following birth. The chicks were subjected to a range of treatments known to affect refractive status, including translucent occlusion, stroboscopic illumination, alteration of the light-dark cycle, intravitreal injection of excitatory amino acids and combinations of these treatments. With occlusion, the central cornea was unaffected or marginally steepened while the anterior chamber and vitreous chamber elongated dramatically to produce a large amount of myopia. Occluder removal (at day 23) produced a slowing of vitreous chamber growth; however, greater refractive recovery (by 44 days) occurred where anterior chambers were shallower at the time of occluder removal (r=-0.87, pCHANGING THE ATTITUDE ABOUT THE OLDER POPULATION: THE ROLE OF GERIATRIC CURRICULUM
Affiliation of Co-Authors
Outline