NERVE FIBER LAYER THICKNESS IN NORMAL BLACKS AS DETERMINED WITH THE NERVE FIBER ANALYZER

Title NERVE FIBER LAYER THICKNESS IN NORMAL BLACKS AS DETERMINED WITH THE NERVE FIBER ANALYZER
Author, Co-Author Ricky Alaniz, Charles Wormington
Topic
Year
1997
Day
Monday
Program Number
Poster 108
Room
Exhibit Hall
Affiliation
Pennsylvania College of Optometry
Abstract PURPOSE: To establish normal values for nerve layer thickness in black subjects with no known eye disease.

METHOD. The right eye from each of ten black subjects with no known eye disease was imaged with the Nerve Fiber Analyzer II (Laser Diagnostic Technologies, Inc., San Diego, CA). Mean age of subjects +/- SD was 40+/-12.8 years (range 25-62 years). Three polarization images were obtained from a 15 degree retinal area centered on the optic nerve head (ONH). The phase shift in the polarization was measured in an annulus 1.7 disc diameters from the ONH. Analysis included breaking the annulus up into 4 sectors (temporal: 0-45 and 315-360 degrees; superior: 45-135 degrees; nasal: 135-225 degrees; and inferior: 225-315 degrees) as well as 36 wedges 10-degrees wide. Red-free fundus photos and threshold visual fields were obtained from all subjects. RESULTS. The measured retinal nerve fiber layer (RNFL) thickness for the superior, inferior, nasal and temporal sectors was 82+/-32, 93+/-26, 62+/-22, and 52+/-22 micrometers, respectively. The mean peaks +/- SD in RNFL thickness in the superior and inferior sectors were 95+/-31 micrometers at 110 degrees and 105+/-22 micrometers at 330 degrees, respectively. CONCLUSIONS. The normative data presented in this poster are part of a long-term study. This study will allow comparison with glaucomatous subjects to see if the technique can be used for early diagnosis. The large standard deviations may hamper its use for this purpose.
Affiliation of Co-Authors
Outline