OPTICAL ENSEMBLE ANALYSIS OF THREE ASPHERIC IOL PERFORMANCE

Title OPTICAL ENSEMBLE ANALYSIS OF THREE ASPHERIC IOL PERFORMANCE
Author, Co-Author Huawei Zhao
Topic
Year
2008
Day
Friday
Program Number
85244
Room
Affiliation
Abbott Medical Optics, Inc.
Abstract PURPOSE: To examine the performance of three aspheric intraocular lenses (IOL) using a clinically-oriented Monte Carlo ensemble analysis of post-operative ocular parameters.

METHODS: Monte Carlo analysis was used to test the optical performance of three aspheric IOLs (an aberration-free silicone IOL that corrects only the lens spherical aberration (SA), a partial correction acrylic IOL that partially corrects ocular SA, and a full correction acrylic IOL that corrects for the average SA of pseudophakic eyes) by computing their MTF values from an ensemble of clinically-relevant ocular parameters including corneal power and asphericity, pupil size and decentration, IOL decentration and tilt. A typical silicone spherical IOL was used as a control for comparisons. Calculations were performed using ZEMAX (ZEMAX Development Corporation, Bellevue, WA, USA), the Liou-Brennan finite model eye (JOSA; 14(8): 1684-95) and the Piers-Norrby-Mester average cornea eye model (Optics Letters; 29(7): 733-735).

RESULTS: With pseudophakic eyes assembled with sampled ocular parameters, the residual average ocular SA [average (one standard deviation)] for a 6mm pupil was 0.35 μm (0.09 μm) for the control compared to 0.25 μm (0.09 μm) for the aberration free IOL; 0.09 μm (0.09 μm) for the partial correction IOL; and 0.00 μm (0.09 μm) for the full correction IOL. The full correction IOL performed significantly better than the control in mesopic light. The partial correction aspheric IOL made from a different acrylic, as well as the aberration-free IOL, performed better than the control, but the level of improvement was not deemed to be significant.

CONCLUSIONS: The simulated post-op ocular aberration is consistent with published distributions. All three aspheric IOLs perform better on average than a typical spherical IOL in mesopic light but with different significance and benefit levels over the simulated population. The aspheric IOL with less material dispersion and targeting full correction of ocular SA provided the best possible optical performance on average in the pseudophakic eyes.
Affiliation of Co-Authors
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