TEAR IgE LEVELS IN PATIENTS SIMULTANEOUSLY WEARING DAILY WEAR AND EXTENDED WEAR DISPOSABLE CONTACT LENSES

Title TEAR IgE LEVELS IN PATIENTS SIMULTANEOUSLY WEARING DAILY WEAR AND EXTENDED WEAR DISPOSABLE CONTACT LENSES
Author, Co-Author Jay Tanner, Kurt Moody, Frank Bucci, Jr.
Topic
Year
1992
Day
Saturday
Program Number
Poster 13
Room
Great Hall
Affiliation
Abstract Fourteen patients wearing a disposable contact lens as a daily wear lens in one eye, and as an extended wear lens in the other eye, had tear IgE levels measured at a baseline visit and at 13 follow-up visits over four weeks. A symptom questionnaire and a patient preference evaluation were completed at each visit. Multiple regression analyses for tear IgE levels against numerous independent variables, including overall lens preference, lens wearing mode, brand of disposable lens, history of allergies, and the level and progression of various symptoms, was performed. Statistical analysis revealed that 100% of patients with a simultaneous bilateral elevation of IgE at any follow-up visit had reported a positive history of allergies. A high rate of false negative IgE readings was suggested by an unpatterned and statistically non-normal distribution of the elevated IgE readings. This is likely explained by a conditioned tearing reflex which developed as a result of the repeated measurements inherent in the design of this study. Diluted tear IgE concentrations may have masked the true relationship between IgE and other tested variables. Lens comfort was the strongest variable (pPHANTOM CONTOUR ILLUSION LETTER TEST
Affiliation of Co-Authors
Outline