TOTAL AMINO ACID DEPOSITION ON SOFT CONTACT LENSES: A COMPARISON STUDY BETWEEN ATLAFILCON AND BUFILCON LENSES

Title TOTAL AMINO ACID DEPOSITION ON SOFT CONTACT LENSES: A COMPARISON STUDY BETWEEN ATLAFILCON AND BUFILCON LENSES
Author, Co-Author John McNally, Earl McCraw, Ph. D., R. Bauman
Topic
Year
1992
Day
Sunday
Program Number
Poster 5
Room
Great Hall
Affiliation
Abstract Protein deposition on hydrogel contact lenses has been implicated in lens spoilage and lens-induced complications. Previous studies have shown a correlation primarily between water content and protein deposition on hydrogel contact lenses. The purpose of this study was to compare the clinical protein deposition of a new high water, non-ionic contact lens material (FDA type II), atlafilcon, to that of a low water, non-ionic material (FDA type I), crofilcon. Sixty-eight patients were dispensed one atlafilcon lens and one crofilcon lens in a 90-day contralateral wear study during which no enzyme component was used in their lens care regimens. Lenses were analyzed for total protein content as measured by the amino acid method of Payor, et. al. [Am. Acad. Opt. Academy 1991]. Atlafilcon lenses were shown to have lower total protein when all age-matched pairs that had been worn for 80 - 120 days were analyzed (atlafilcon = 2.06, s.d. = 1.73 ug, crofilcon = 5.16, s.d. = 3.32 ug, paired t-test, pPARAMETER ALTERATIONS CAN AFFECT COMFORT OF RIGID GAS PERMEABLE LENSES
Affiliation of Co-Authors
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