YIELD OF LABORATORY TESTING FOR ANTERIOR UVEITIS IN AN AFRICAN AMERICAN URBAN VA POPULATION

Title YIELD OF LABORATORY TESTING FOR ANTERIOR UVEITIS IN AN AFRICAN AMERICAN URBAN VA POPULATION
Author, Co-Author Sara Aggarwal, Beth Swetland, Victoria Trieu, Michelle Marciniak, Thomas Stelmack
Topic
Year
1998
Day
Sunday
Program Number
Poster 63
Room
Grand Ballroom
Affiliation
Department of Veterans Affairs Chicago Health Care System
Abstract Purpose.This retrospective, descriptive study reports the percent yield of a comprehensive laboratory work-up in patients presenting with anterior uveitis. Methods. Records from patients seen at West Side VAMC eye clinic, within the last three years, were retrospectively reviewed. Inclusion criteria were defined as all patients who were diagnosed with anterior uveitis and underwent a comprehensive laboratory work-up. A comprehensive laboratory work-up was defined as including Angiotensin Converting Enzyme (ACE), Serum Lysozyme (SL), Rapid Plasma Reagin (RPR), Fluorescent Treponemal Antibody Absorption Test (FTA-Abs) or equivalent, Anti-Nuclear Antibody (ANA) and Complete Blood Count with Differential (CBC). Comprehensive lab work-up was done in patients with recurrent, recalcitrant, granulomatous or severe uveitis. A positive result on any one particular test was considered as a positive yield. Patients who did not receive a comprehensive laboratory work-up (as previously defined), and those patients presenting with either a surgical or non-surgical traumatic uveitis were excluded. Results from additional laboratory tests, including Chest X-Ray (CXR), Sacroiliac X-Ray, Purified Protein Derivative (PPD), Histocompatibility Locus Antigen serotype B27 (HLA-B27), Rheumatoid Factor (RF) and Erythrocyte Sedimentation Rate (ESR) were also recorded. Results. A total of 106 patients were identified with anterior uveitis. Of these, 30 patients had completed the comprehensive lab work-up. Positive results were found from this initial work-up in 10 (33%) patients. Additional testing was done in 18 patients and had a 78% yield. Overall, lab work-up had a 63% yield. ANA and treponemal specific testing for syphilis had the highest yields, with 17% and 20%, respectively. CBC with differential was not contributory in any case. Conclusion. Laboratory results should always be correlated with both the physical examination and history. The yield of lab testing in carefully selected case
Affiliation of Co-Authors Department of Veterans Affairs Chicago Health Care System, Illinois College of Optometry, Department of Veterans Affairs Chicago Health Care System
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