Comparison of cysts in red and green images for diabetic macular edema

Mastour Alhamami

Abstract

Purpose: To improve the detection of macular cyst with photoscreening, we tested whether in a population of largely minority patients the red channel image from a color fundus camera visualizes cysts in diabetic macular edema better than the green channel image. In assessing diabetic retinas for clinically significant macular edema, the presence of cysts must be judged with respect to the central macula. Some grading programs use red free images, often derived from green channel images, to enhance visualization of retinal vessel damage or macular pigment, but some red and near infrared instruments have detected cysts better than short wavelength techniques.

Methods: We evaluated macular cysts in 13 diabetic patients diagnosed with clinically significant macular edema, age range 33-68 years. Diabetic patients were selected from the screening study of >2000 underserved patients seen at Eastmont Wellness Center, Oakland, CA. Patients underwent photoscreening with a nonmydriatic color fundus camera (Canon Cr-DGi, Tokyo, Japan) and SD-OCT (iVue, Optovue Inc, Fremont, CA). The color fundus images for those patients were transformed into red and green channels to evaluate the appearance of macular cysts in red channel images and green channel images. The region of each cyst was compared SD-OCT scans (Adobe Photoshop CS5.1, San Jose, CA). Only cysts touching the central 1 mm around the fixation from the SD-OCT scans were sampled.

Results: The average size of retinal cysts in red channel images, 124.57 µm (±106.96), was significantly greater than in green channel, 59.44 µm (±76.6), (p<0.006). Entire cysts could not be seen in 5 eyes in the green channel images.

Conclusions: Our results indicate that the grading of cysts in the central macular might be improved by incorporating red channel images. There are a number of potential factors that could make cysts less visible in the green channel images, including poorer light penetration through to the deeper retina or macular pigment. Anterior segment issues impact more on green channel images. This population includes mostly minority patients who have dark fundi, and darker images.

Details

Year: 2014

Program Number: 140042

Resource Type: Scientific Program

Author Affiliation: n/a

Co-Authors: Ann Elsner, Matthew Muller, Karthikeyan Baskaran, Thomas Gast, Taras Litvin, Glen Ozawa, Jorge Cuadros, Bryan Haggerty, Victor Malinovsky, Christopher Clark, Shane Brahm, Stuart Young

Co-Author Affiliation: Indiana University School of Optometry, Aeon Imaging, Indiana University School of Optometry, Indiana University School of Optometry, University of California Berkeley, School of Optometry, University of California Berkeley, School of Optometry, University of California Berkeley, School of Optometry, Indiana University School of Optometry, Indiana University School of Optometry, Indiana University School of Optometry, Indiana University School of Optometry, Indiana University School of Optometry

Room: Room 201-203