EFFECTS OF AGING ON CORNEAL STRUCTURE AND FUNCTION

Kenneth Polse

Abstract

In a previous study of 8 young and 8 older volunteers, mean ages 24.4 and 71.9 years, we found that Corneal Hydration Control (CHC), measured by the Percent Recovery Per Hour (PRPH) during exponential recovery after induced corneal swelling, was faster for younger subjects at 58.9 %/hr than older subjects at 34.2%/hr (p=0.0002)1. A larger study of CHC with 54 males and 67 females, distributed over the age range from 25 to 82, has now been completed to check earlier findings, examine trends in PRPH with age, and investigate gender differences in PRPH. The decline in mean PRPH per 50 years, using parallel linear trends for both genders, is 10.65 (pENDOTHELIAL ADHESION-MORPHOLOGICAL CONSIDERATIONS

Details

Year: 1992

Program Number: 3:15 pm

Author Affiliation: n/a

Co-Authors: Richard Brand, Reuben Rivera, Cheslyn Gan, Andrew Graham

Co-Author Affiliation: n/a

Room: Scotland B