THE TEAR FERNING TEST AND CLINICO-CHEMICAL TEAR ANALYSIS OF THE DRY EYE SUBJECT

Yvonne Johnson

Abstract

This study investigated tear ferning results and clinical and chemical analysis of tears in dry eye subjects. Tests included non- invasive break-up time (nibut), fluorescein break- up time (flbut), tear ferning, total tear protein, and high performance liquid chromatography. Five dry eye subjects identified by positive rose bengal staining were compared to 35 normal, non- contact lens wearing control subjects. For the dry eye subjects the nibut was significantly shorter (p=.01), the ferning pattern was significantly poorer (p=.04), and lactoferrin concentration was significantly higher (p=.02) than the controls. A trend for a decreased concentration of high molecular weight protein fraction was seen for the dry eye subjects (p=.052). Understanding the underlying mechanism for tear film abnormalities associated with the dry eye may be explained by chemical analysis and diagnostically supported by the ferning test.

Details

Year: 1992

Program Number: Poster 28

Author Affiliation: n/a

Co-Authors: n/a

Co-Author Affiliation: n/a

Room: Great Hall