VISUAL DYSFUNCTION IN PARKINSON'S DISEASE

Brian Kaskie

Abstract

Patients with Parkinson's disease (PD) frequently exhibit significant contrast sensitivity deficits which appear to be related to dopamine depletion in either the retina, lateral geniculate nucleus or primary visual cortex. The present study was designed to determine whether visual loss in Parkinson's disease affects other aspects of visual performance. Specifically, we evaluated motion detection and orientation discrimination thresholds in 11 patients with PD and 22 healthy adults of similar age. All of the subjects had visual acuity of 20/30 or better and none had any evidence of significant cognitive impairment. Motion detection was assessed using a high contrast, random dot, direction discrimination paradigm (Trick & Silverman, Neurology, 1991). Orientation discrimination thresholds were determined for the detection of misalignment in high contrast horizontal and vertical achromatic gratings (3.6 cycles/deg) generated on a Picasso visual stimulator. Our results indicated a significant difference (pEFFECTS OF ULTRAVIOLET RADIATION ON THE SHEDDING RATE OF THE CORNEAL EPITHELIUM IN VITRO

Details

Year: 1992

Program Number: Poster 32

Author Affiliation: n/a

Co-Authors: Gary Trick, University of Montreal and Department of Ophthalmology Maison, Montreal, Canada, Scott Steinman

Co-Author Affiliation: n/a

Room: Great Hall