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Chorioretinitis occurs from numerous etiologies. Common differentials include toxoplasmosis, sarcoidosis, tuberculosis, and syphilis. Cytomegalovirus (CMV) is a less encountered cause.
This patient presented with severely decreased vision in her left eye. She denied flashes of light or pain. Her medical history was significant for diabetes and breast cancer. Fundus examination revealed vitritis and chorioretinitis. The initial working diagnosis was toxoplasmosis. Lab work, however, returned positive for active CMV infection.
It is important to consider all aspects of a patient’s medical history. This patient contracted CMV due to immunosuppressive effects of chemotherapy. Intravitreal antiviral medications are often an effective treatment.